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A Cell-based PDE4 Assay in 1536-well Plate format for High Throughput Screening

The cyclic nucleotide phosphodiesterases (PDEs) are intracellular enzymes that catalyze the hydrolysis of 3', 5'-cyclic nucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), to their corresponding 5'-nucleotide monophosphates. These enzy...

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Main Authors: Titus, Steven A., Li, Xiao, Southall, Noel, Lu, Jianming, Inglese, James, Brasch, Michael, Austin, Christopher P., Zheng, Wei
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661206/
https://ncbi.nlm.nih.gov/pubmed/18591513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057108319977
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