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Immunization with Radiation-Attenuated Plasmodium berghei Sporozoites Induces Liver cCD8α(+)DC that Activate CD8(+)T Cells against Liver-Stage Malaria
Immunization with radiation (γ)-attenuated Plasmodia sporozoites (γ-spz) confers sterile and long-lasting immunity against malaria liver-stage infection. In the P. berghei γ-spz model, protection is linked to liver CD8(+) T cells that express an effector/memory (T(EM)) phenotype, (CD44(hi)CD45RB(lo)...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661143/ https://ncbi.nlm.nih.gov/pubmed/19347042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005075 |
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