Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen

We recently identified novel Plasmodium berghei (Pb) liver stage (LS) genes that as DNA vaccines significantly reduce Pb LS parasite burden (LPB) in C57Bl/6 (B6) mice through a mechanism mediated, in part, by CD8 T cells. In this study, we sought to determine fine antigen (Ag) specificities of CD8 T...

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Publicat a:Front Immunol
Autors principals: Pichugin, Alexander, Zarling, Stasya, Perazzo, Leah, Duffy, Patrick Emmet, Ploegh, Hidde Lolke, Krzych, Urszula
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796907/
https://ncbi.nlm.nih.gov/pubmed/29434602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00091
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