HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome

BACKGROUND: Nuclear import of the HIV-1 reverse transcription complex (RTC) is critical for infection of non dividing cells, and importin 7 (imp7) has been implicated in this process. To further characterize the function of imp7 in HIV-1 replication we generated cell lines stably depleted for imp7 a...

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Bibliografiske detaljer
Main Authors: Zaitseva, Lyubov, Cherepanov, Peter, Leyens, Lada, Wilson, Sam J, Rasaiyaah, Jane, Fassati, Ariberto
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660290/
https://ncbi.nlm.nih.gov/pubmed/19193229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-11
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