Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells

Selectins facilitate metastasis and tumor cell arrest in the microvasculature by mediating binding of selectin-expressing host cells to ligands on tumor cells. We recently identified CD44 variant isoforms as functional P-, but not E-/L-, selectin ligands on colon carcinoma cells. Furthermore, a ∼180...

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Bibliographic Details
Main Authors: Thomas, Susan N., Schnaar, Ronald L., Konstantopoulos, Konstantinos
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
Subjects:
Extracellular Matrix, Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660269/
https://ncbi.nlm.nih.gov/pubmed/19118161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00472.2008
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