Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice

The cytotoxic T cell (CT) GalNAc transferase, or Galgt2, is a UDP-GalNAc:β1,4-N-acetylgalactosaminyltransferase that is localized to the neuromuscular synapse in adult skeletal muscle, where it creates the synaptic CT carbohydrate antigen {GalNAcβ1,4[NeuAc(orGc)α2, 3]Galβ1,4GlcNAcβ-}. Overexpression...

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Detalhes bibliográficos
Main Authors: Martin, Paul T., Xu, Rui, Rodino-Klapac, Louise R., Oglesbay, Elaine, Camboni, Marybeth, Montgomery, Chrystal L., Shontz, Kim, Chicoine, Louis G., Clark, K. Reed, Sahenk, Zarife, Mendell, Jerry R., Janssen, Paul M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Muscle Cell Biology and Cell Motility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660265/
https://ncbi.nlm.nih.gov/pubmed/19109526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00456.2008
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