Simvastatin enhances bone marrow stromal cell differentiation into endothelial cells via notch signaling pathway

Bone marrow stromal cells (BMSCs) are capable of differentiating into multiple cell lineages including endothelial cells. Simvastatin, an HMG-CoA reductase inhibitor that is used as a cholesterol-lowering agent, promotes endothelial differentiation from epithelial progenitor cells (EPC). The Notch s...

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Detalhes bibliográficos
Main Authors: Xu, Jian, Liu, Xinfeng, Chen, Jieli, Zacharek, Alex, Cui, Xu, Savant-Bhonsale, Smita, Liu, Zhenguo, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Growth, Differentiation, and Apoptosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660258/
https://ncbi.nlm.nih.gov/pubmed/19109527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00310.2008
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