Nitric Oxide Donor Upregulation of Stromal Cell-Derived Factor-1/Chemokine (CXC Motif) Receptor 4 Enhances Bone Marrow Stromal Cell Migration into Ischemic Brain After Stroke

Stromal cell-derived factor-1 (SDF1) and its chemokine (CXC motif) receptor 4 (CXCR4), along with matrix metalloproteinases (MMPs), regulate bone marrow stromal cell (BMSC) migration. We tested the hypothesis that a nitric oxide donor, DETA-NONOate, increases endogenous ischemic brain SDF1 and BMSC...

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Detalhes bibliográficos
Main Authors: Cui, Xu, Chen, Jieli, Zacharek, Alex, Li, Yi, Roberts, Cynthia, Kapke, Alissa, Savant-Bhonsale, Smita, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792206/
https://ncbi.nlm.nih.gov/pubmed/17641243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2007-0169
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