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Transcriptional regulation of IL-6 in bile duct epithelia by extracellular ATP

The inflammatory cytokine IL-6 is essential for cell survival after liver injury. Bile duct epithelia (BDE) markedly upregulate IL-6 release after liver injury, but the mechanisms regulating this have not been defined. Purinergic signals induce multiple potent downstream effects in BDE, so the goals...

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Detalhes bibliográficos
Main Authors: Yu, Jin, Sheung, Nina, Soliman, Elwy M., Spirli, Carlo, Dranoff, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660176/
https://ncbi.nlm.nih.gov/pubmed/19136380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90502.2008
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