Structural plasticity of an acid-activated chaperone allows promiscuous substrate binding

HdeA has been shown to prevent acid-induced aggregation of proteins. With a mass of only 9.7 kDa, HdeA is one of the smallest chaperones known. Unlike other molecular chaperones, which are typically complex, multimeric ATP-dependent machines, HdeA is known to undergo an acid-induced dimer to monomer...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Tapley, Timothy L., Körner, Jan L., Barge, Madhuri T., Hupfeld, Julia, Schauerte, Joseph A., Gafni, Ari, Jakob, Ursula, Bardwell, James C. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660062/
https://ncbi.nlm.nih.gov/pubmed/19321422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811811106
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller