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Structural plasticity of an acid-activated chaperone allows promiscuous substrate binding
HdeA has been shown to prevent acid-induced aggregation of proteins. With a mass of only 9.7 kDa, HdeA is one of the smallest chaperones known. Unlike other molecular chaperones, which are typically complex, multimeric ATP-dependent machines, HdeA is known to undergo an acid-induced dimer to monomer...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660062/ https://ncbi.nlm.nih.gov/pubmed/19321422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811811106 |
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