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Different Domains Regulate Homomeric and Heteromeric Complex Formation among Type I and Type II Transforming Growth Factor-β Receptors
Transforming growth factor-β (TGF-β) binds to and signals via two serine-threonine kinase receptors, type I (TβRI) and type II (TβRII). The oligomerization of TGF-β receptors modulates ligand binding and receptor trafficking and may contribute to signal diversification. However, numerous features of...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659930/ https://ncbi.nlm.nih.gov/pubmed/19147499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809215200 |
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