Different Domains Regulate Homomeric and Heteromeric Complex Formation among Type I and Type II Transforming Growth Factor-β Receptors

Transforming growth factor-β (TGF-β) binds to and signals via two serine-threonine kinase receptors, type I (TβRI) and type II (TβRII). The oligomerization of TGF-β receptors modulates ligand binding and receptor trafficking and may contribute to signal diversification. However, numerous features of...

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Hlavní autoři: Rechtman, Maya Mouler, Nakaryakov, Alex, Shapira, Keren E., Ehrlich, Marcelo, Henis, Yoav I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659930/
https://ncbi.nlm.nih.gov/pubmed/19147499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809215200
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