Oncolytic HSV-1 Infection of Tumors Induces Angiogenesis and Upregulates CYR61

Oncolytic viral therapy is under evaluation for toxicity and efficacy in clinical trials relating to several different tumors. We report a significant increase in the angiogenic index of oncolytic virus (OV)-treated glioma-matrigel implants (2.83-fold, P < 0.02). In a rat intracranial glioma mode...

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Detalhes bibliográficos
Main Authors: Kurozumi, Kazuhiko, Hardcastle, Jayson, Thakur, Roopa, Shroll, Joshua, Nowicki, Michal, Otsuki, Akihiro, Chiocca, E Antonio, Kaur, Balveen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659780/
https://ncbi.nlm.nih.gov/pubmed/18545226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.112
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