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Roles of the Werner syndrome RecQ helicase in DNA replication
Congenital deficiency in the WRN protein, a member of the human RecQ helicase family, gives rise to Werner syndrome, a genetic instability and cancer predisposition disorder with features of premature aging. Cellular roles of WRN are not fully elucidated. WRN has been implicated in telomere maintena...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659608/ https://ncbi.nlm.nih.gov/pubmed/18722555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.07.017 |
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