Optimal window of caloric restriction onset limits its beneficial impact upon T cell senescence in primates

We have recently shown in non-human primates that caloric restriction (CR) initiated during adulthood can delay T-cell aging and preserve naïve CD8 and CD4 T cells into advanced age. An important question is whether CR can be initiated at any time in life, and whether age at the time of onset would...

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Bibliografiske detaljer
Main Authors: Messaoudi, Ilhem, Fischer, Miranda, Warner, Jessica, Park, Buyng, Mattison, Julie, Ingram, Donald K., Totonchy, Thomas, Mori, Motomi, Nikolich-Zugich, Janko
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659568/
https://ncbi.nlm.nih.gov/pubmed/19032694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2008.00440.x
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