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Upregulation of p21(Waf1/Cip1) expression in vivo by butyrate administration can be chemoprotective or chemopromotive depending on the lipid component of the diet

The overall goal of this research was to separate out the effects of butyrate from its fiber source and determine in vivo if it upregulates colonic histone acetylation, p21(Waf1/Cip1) expression (p21) and apoptosis and if this sequela of events is protective against aberrant crypt foci (ACF) formati...

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Detalles Bibliográficos
Main Authors: Crim, Kristy Covert, Sanders, Lisa M., Hong, Mee Young, Taddeo, Stella S., Turner, Nancy D., Chapkin, Robert S., Lupton, Joanne R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659529/
https://ncbi.nlm.nih.gov/pubmed/18567619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn144
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