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Syntheses and Biological Evaluation of B-Ring-Modified Analogs of Dafachronic Acid A
[Image: see text] Synthesis and testing of dafachronic acid A (1) and its derivatives 2 and 3 have revealed that 1, and not a further oxidation product, is the natural ligand for the DAF-12 receptor of C. elegans.
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659505/ https://ncbi.nlm.nih.gov/pubmed/18642835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol801425v |
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