Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major

Ecotin is a potent inhibitor of family S1A serine peptidases, enzymes lacking in the protozoan parasite Leishmania major. Nevertheless, L. major has three ecotin-like genes, termed inhibitor of serine peptidase (ISP). ISP1 is expressed in vector-borne procyclic and metacyclic promastigotes, whereas...

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Detalhes bibliográficos
Main Authors: Eschenlauer, Sylvain C P, Faria, Marilia S, Morrison, Lesley S, Bland, Nicolas, Ribeiro-Gomes, Flavia L, DosReis, George A, Coombs, Graham H, Lima, Ana Paula C A, Mottram, Jeremy C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659362/
https://ncbi.nlm.nih.gov/pubmed/19016791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2008.01243.x
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