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A potential role for ICP, a leishmanial inhibitor of cysteine peptidases, in the interaction between host and parasite
The biological role of a natural inhibitor of cysteine peptidases (designated ICP) of Leishmania has been investigated by genetic manipulation of the parasite. Null mutants grew normally in vitro, were as infective to macrophages in vitro as wild-type parasites, but had reduced infectivity to mice....
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2244714/ https://ncbi.nlm.nih.gov/pubmed/15554964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2004.04355.x |
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