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The Drosophila melanogaster Gene cg4930 Encodes a High Affinity Inhibitor for Endonuclease G

Endonuclease G (EndoG) is a mitochondrial enzyme believed to be released during apoptosis to participate in the degradation of nuclear DNA. This paper describes a Drosophila protein, EndoGI, which inhibits EndoG specifically. EndoG and EndoGI associate with subpicomolar affinity, forming a 2:1 compl...

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Detalhes bibliográficos
Main Authors: Temme, Claudia, Weissbach, Rebekka, Lilie, Hauke, Wilson, Clive, Meinhart, Anton, Meyer, Sylke, Golbik, Ralph, Schierhorn, Angelika, Wahle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659192/
https://ncbi.nlm.nih.gov/pubmed/19129189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808319200
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