Erythroid-specific Human Factor IX Delivery From In Vivo Selected Hematopoietic Stem Cells Following Nonmyeloablative Conditioning in Hemophilia B Mice

We have developed a lentiviral vector system for human factor IX (hFIX) gene transfer in hematopoietic stem cells (HSCs) that provides erythroid cell-derived systemic protein delivery following nonmyeloablative conditioning and in vivo methylguanine methyltransferase (MGMT) drug selection. After bon...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chang, Alex H, Stephan, Matthias T, Lisowski, Leszek, Sadelain, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658893/
https://ncbi.nlm.nih.gov/pubmed/18682698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.161
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados