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Erythroid-specific Human Factor IX Delivery From In Vivo Selected Hematopoietic Stem Cells Following Nonmyeloablative Conditioning in Hemophilia B Mice

We have developed a lentiviral vector system for human factor IX (hFIX) gene transfer in hematopoietic stem cells (HSCs) that provides erythroid cell-derived systemic protein delivery following nonmyeloablative conditioning and in vivo methylguanine methyltransferase (MGMT) drug selection. After bon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chang, Alex H, Stephan, Matthias T, Lisowski, Leszek, Sadelain, Michel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658893/
https://ncbi.nlm.nih.gov/pubmed/18682698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.161
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