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IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice

Resistance to leishmaniasis in C57BL/6 mice depends on Th1/Tc1 cells. BALB/c mice preferentially develop Th2 immunity and succumb to infection. We now assessed the role of IL-17 in cutaneous leishmaniasis. During the course of L. major infection, BALB/c CD4 cells and neutrophils produced increased a...

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Detalhes bibliográficos
Main Authors: Kostka, Susanna Lopez, Dinges, Stephanie, Griewank, Klaus, Iwakura, Yoichiro, Udey, Mark C., von Stebut, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658650/
https://ncbi.nlm.nih.gov/pubmed/19234200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0713598
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