Interleukin-27 (IL-27) Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17–Neutrophil Response

The relationship established between Leishmania infantum and the vertebrate host can lead to a self-healing infection or to the manifestation of visceral leishmaniasis, a chronic systemic infection associated with high rates of mortality. We hypothesized that regulatory cytokines, such as interleuki...

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Udgivet i:Infect Immun
Main Authors: Quirino, Gustavo F. S., Nascimento, Manuela S. L., Davoli-Ferreira, Marcela, Sacramento, Lais A., Lima, Mikhael H. F., Almeida, Roque P., Carregaro, Vanessa, Silva, João Santana
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962641/
https://ncbi.nlm.nih.gov/pubmed/27245409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00283-16
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