Interleukin 1α Promotes Th(1) Differentiation and Inhibits Disease Progression in Leishmania major–susceptible BALB/c Mice

Protective immunity against pathogens such as Leishmania major is mediated by interleukin (IL)-12–dependent Th(1)-immunity. We have shown previously that skin-dendritic cells (DCs) from both resistant C57BL/6 and susceptible BALB/c mice release IL-12 when infected with L. major, and infected BALB/c...

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Main Authors: von Stebut, Esther, Ehrchen, Jan M., Belkaid, Yasmine, Kostka, Susanna Lopez, Mölle, Katharina, Knop, Jürgen, Sunderkötter, Cord, Udey, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194079/
https://ncbi.nlm.nih.gov/pubmed/12860932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030159
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