Senescent BALB/c Mice Are Able To Develop Resistance to Leishmania major Infection

Aging has been associated with a decline in immunocompetence and resistance to infections, partially due to dysregulated NO production by macrophages and deficits in mounting Th2 cell responses. We wondered if these alterations would reverse the immune response in experimental leishmaniasis. Bone-ma...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Ehrchen, Jan, Sindrilaru, Anca, Grabbe, Stephan, Schönlau, Frank, Schlesiger, Christian, Sorg, Clemens, Scharffetter-Kochanek, Karin, Sunderkötter, Cord
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517419/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15322004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.9.5106-5114.2004
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