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Variation in the ICAM1 gene is not associated with severe malaria phenotypes

Evidence from autopsy, mouse-model and in vitro binding studies suggests that adhesion of erythrocytes infected with Plasmodium falciparum to the human host intercellular adhesion molecule (ICAM)-1 receptor is important in the pathogenesis of severe malaria. Previous association studies between poly...

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Bibliografiska uppgifter
Huvudupphovsmän: Fry, Andrew E., Auburn, Sarah, Diakite, Mahamadou, Green, Angela, Richardson, Anna, Wilson, Jonathan, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Griffiths, Michael J., Peshu, Norbert, Williams, Thomas N., Marsh, Kevin, Molyneux, Malcolm E., Taylor, Terrie E., Rockett, Kirk A., Kwiatkowski, Dominic P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657869/
https://ncbi.nlm.nih.gov/pubmed/18528404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2008.38
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