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The p53 family and programmed cell death

The p53 tumor suppressor continues to hold distinction as the most frequently mutated gene in human cancer. The ability of p53 to induce programmed cell death, or apoptosis, of cells exposed to environmental or oncogenic stress constitutes a major pathway whereby p53 exerts its tumor suppressor func...

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Autori principali: Pietsch, E. Christine, Sykes, Stephen M., McMahon, Steven B., Murphy, Maureen E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657599/
https://ncbi.nlm.nih.gov/pubmed/18955976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.315
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