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Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine

The highly conserved 90 kDa heat shock protein (Hsp90) chaperones use ATP to regulate the stability and activity of many signalling molecules like protein kinases and transcription factors. Studies using crystallography, electron microscopy and small-angle X-ray scattering yielded controversial resu...

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Bibliografski detalji
Glavni autori: Graf, Christian, Stankiewicz, Marta, Kramer, Günter, Mayer, Matthias P
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657576/
https://ncbi.nlm.nih.gov/pubmed/19165152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.306
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