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Normal development and activation but altered cytokine production of Fyn-deficient CD4(+) T cells

The Src family kinase, Fyn, is expressed in T cells and has been shown to phosphorylate proteins involved in TCR signaling, cytoskeletal reorganization and IL-4 production. Fyn-deficient mice have greatly decreased numbers of NKT cells, and have thymocytes and T cells with compromised responses foll...

詳細記述

保存先:
書誌詳細
主要な著者: Mamchak, Alusha A., Sullivan, Brandon M., Hou, Baidong, Lee, Linda M., Gilden, Julia K., Krummel, Matthew F., Locksley, Richard M., DeFranco, Anthony L.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657555/
https://ncbi.nlm.nih.gov/pubmed/18832694
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