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Telomerase insufficiency in rheumatoid arthritis
In rheumatoid arthritis (RA), chronically stimulated T lymphocytes sustain tissue-destructive joint inflammation. Both naïve and memory T cells in RA are prematurely aged with accelerated loss of telomeres suggesting excessive proliferative pressure or inadequate telomeric maintenance. Upon stimulat...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657451/ https://ncbi.nlm.nih.gov/pubmed/19255426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811332106 |
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