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The structure of CDK4/cyclin D3 has implications for models of CDK activation

Cyclin-dependent kinase 4 (CDK4)/cyclin D complexes are expressed early in the G(1) phase of the cell cycle and stimulate the expression of genes required for G(1) progression by phosphorylation of the product of the retinoblastoma gene, pRb. To elaborate the molecular pathway of CDK4 activation and...

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書誌詳細
主要な著者: Takaki, T., Echalier, A., Brown, N. R., Hunt, T., Endicott, J. A., Noble, M. E. M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657433/
https://ncbi.nlm.nih.gov/pubmed/19237555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809674106
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