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The structure of CDK4/cyclin D3 has implications for models of CDK activation

Cyclin-dependent kinase 4 (CDK4)/cyclin D complexes are expressed early in the G(1) phase of the cell cycle and stimulate the expression of genes required for G(1) progression by phosphorylation of the product of the retinoblastoma gene, pRb. To elaborate the molecular pathway of CDK4 activation and...

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Bibliographische Detailangaben
Hauptverfasser: Takaki, T., Echalier, A., Brown, N. R., Hunt, T., Endicott, J. A., Noble, M. E. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657433/
https://ncbi.nlm.nih.gov/pubmed/19237555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809674106
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