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Bimodal protein solubility distribution revealed by an aggregation analysis of the entire ensemble of Escherichia coli proteins

Protein folding often competes with intermolecular aggregation, which in most cases irreversibly impairs protein function, as exemplified by the formation of inclusion bodies. Although it has been empirically determined that some proteins tend to aggregate, the relationship between the protein aggre...

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Detalhes bibliográficos
Main Authors: Niwa, Tatsuya, Ying, Bei-Wen, Saito, Katsuyo, Jin, WenZhen, Takada, Shoji, Ueda, Takuya, Taguchi, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657415/
https://ncbi.nlm.nih.gov/pubmed/19251648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811922106
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