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Sequence context effect for hMSH2-hMSH6 mismatch-dependent activation
Numerous DNA mismatches and lesions activate MutS homologue (MSH) ATPase activity that is essential for mismatch repair (MMR). We have found that a mismatch embedded in a nearest-neighbor sequence context containing symmetric 3′-purines (2 × 3′-purines) enhanced, whereas symmetric 3′-pyrimidines (2...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657375/ https://ncbi.nlm.nih.gov/pubmed/19237577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808572106 |
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