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Prostaglandin D(2) inhibits interleukin-1β-induced matrix metalloproteinase-1 and -13 production by human osteoarthritic chondrocytes
OBJECTIVE: To investigate the effects of prostaglandin (PG) D(2) on interleukin-1β (IL-1)-induced matrix metalloproteinase (MMP)-1 and MMP-13 expression in human chondrocytes and the signalling pathways involved in the effects of PGD(2). METHODS: Chondrocytes were stimulated with IL-1 ± PGD(2) and M...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657141/ https://ncbi.nlm.nih.gov/pubmed/18975308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23958 |
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