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Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy
In eukaryotic cells, control mechanisms have developed that restrain cell-cycle transitions in response to stress. These regulatory pathways are termed cell-cycle checkpoints. The G(2)/M checkpoint prevents cells from entering mitosis when DNA is damaged in order to afford these cells an opportunity...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657106/ https://ncbi.nlm.nih.gov/pubmed/19216791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-8 |
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