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Sp1 contributes to radioresistance of cervical cancer through targeting G2/M cell cycle checkpoint CDK1

BACKGROUND/AIMS: Radioresistance remains a significant obstacle in the therapy of cervical cancer, and the mechanism of it is still unclear. We aimed to investigate the role of specificity protein 1 (Sp1) in radioresistance of cervical cancer. METHODS: Sp1 was examined immunohistochemically on tissu...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Principais autores: Deng, Yuan-Run, Chen, Xiao-Jing, Chen, Wei, Wu, Lan-Fang, Jiang, Hui-Ping, Lin, Dan, Wang, Li-Jing, Wang, Wei, Guo, Sui-Qun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610296/
https://ncbi.nlm.nih.gov/pubmed/31303791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S200907
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