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Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency
The efficiency of remyelination decreases with age, but the molecular mechanisms responsible for this decline remain only partially understood. In this study, we show that remyelination is regulated by age-dependent epigenetic control of gene expression. In demyelinated young brains, new myelin synt...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656679/ https://ncbi.nlm.nih.gov/pubmed/19160500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2172 |
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