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Thymulin gene therapy prevents the reduction in circulating gonadotropins induced by thymulin deficiency in mice

Integrity of the thymus during perinatal life is necessary for a proper maturation of the pituitary-gonadal axis in mice and other mammalian species. Thus congenitally athymic (nude) female mice show significantly reduced levels of circulating gonadotropins, a fact that seems to be causally related...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Goya, Rodolfo G., Reggiani, Paula C., Vesenbeckh, Silvan M., Pléau, Jean M., Sosa, Yolanda E., Cónsole, Gloria M., Schade, Rüdiger, Henklein, Peter, Dardenne, Mireille
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656608/
https://ncbi.nlm.nih.gov/pubmed/17389714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00085.2007
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