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Thymulin gene therapy prevents the reduction in circulating gonadotropins induced by thymulin deficiency in mice
Integrity of the thymus during perinatal life is necessary for a proper maturation of the pituitary-gonadal axis in mice and other mammalian species. Thus congenitally athymic (nude) female mice show significantly reduced levels of circulating gonadotropins, a fact that seems to be causally related...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656608/ https://ncbi.nlm.nih.gov/pubmed/17389714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00085.2007 |
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