Neonatal Thymulin Gene Therapy Prevents Ovarian Dysgenesis and Attenuates Reproductive Derangements in Nude Female Mice

Congenitally athymic (nude) female mice show severe ovarian dysgenesis after puberty, which seems to be consequential to a number of neuroendocrine derangements described in these mutants. Thus, considerable evidence suggests that thymulin, a thymic peptide, may be involved in thymus-pituitary commu...

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Detalhes bibliográficos
Main Authors: Reggiani, Paula C., Barbeito, Claudio G., Zuccolilli, Gustavo O., Cónsole, Gloria M., Flamini, Alicia M., Dardenne, Mireille, Goya, Rodolfo G.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Reproduction-Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404341/
https://ncbi.nlm.nih.gov/pubmed/22700775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1183
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