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Neonatal Thymulin Gene Therapy Prevents Ovarian Dysgenesis and Attenuates Reproductive Derangements in Nude Female Mice

Congenitally athymic (nude) female mice show severe ovarian dysgenesis after puberty, which seems to be consequential to a number of neuroendocrine derangements described in these mutants. Thus, considerable evidence suggests that thymulin, a thymic peptide, may be involved in thymus-pituitary commu...

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Main Authors: Reggiani, Paula C., Barbeito, Claudio G., Zuccolilli, Gustavo O., Cónsole, Gloria M., Flamini, Alicia M., Dardenne, Mireille, Goya, Rodolfo G.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404341/
https://ncbi.nlm.nih.gov/pubmed/22700775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1183
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