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Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells

BACKGROUND: D-ribose in cells and human serum participates in glycation of proteins resulting in advanced glycation end products (AGEs) that affect cell metabolism and induce cell death. However, the mechanism by which D-ribose-glycated proteins induce cell death is still unclear. RESULTS: Here, we...

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Detalhes bibliográficos
Main Authors: Wei, Yan, Chen, Lan, Chen, Ji, Ge, Lin, He, Rong Qiao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656460/
https://ncbi.nlm.nih.gov/pubmed/19216769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-10
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