Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients

Treatment of Epstein-Barr virus (EBV)–positive nasopharyngeal carcinoma (NPC) with EBV-specific cytotoxic T cells (EBV-specific CTL) has been promising, producing clinical responses. However, infused EBV-specific CTL did not expand in vivo, likely limiting their antitumor activity. Lymphodepleting p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Louis, Chrystal U., Straathof, Karin, Bollard, Catherine M., Gerken, Claudia, Huls, M. Helen, Gresik, M. Victoria, Wu, Meng-Fen, Weiss, Heidi L., Gee, Adrian P., Brenner, Malcolm K., Rooney, Cliona M., Heslop, Helen E., Gottschalk, Stephen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2009
Aiheet:
Immunobiology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656271/
https://ncbi.nlm.nih.gov/pubmed/18971421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157222
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