JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes

Genomic DNA of African trypanosomes contains a hypermodified thymidine residue termed base J (β-d-glucosyl-HOMedU). This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pat...

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Sonraí Bibleagrafaíochta
Main Authors: Cliffe, Laura J., Kieft, Rudo, Southern, Timothy, Birkeland, Shanda R., Marshall, Marion, Sweeney, Kate, Sabatini, Robert
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2009
Ábhair:
Nucleic Acid Enzymes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655668/
https://ncbi.nlm.nih.gov/pubmed/19136460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1067
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