The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase

Trypanosomatids contain an unusual DNA base J (β-d-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have searched for enzymes that catalyze J biosynthesis. We present evidence that a protein that binds to J...

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Detalhes bibliográficos
Main Authors: Yu, Zhong, Genest, Paul-André, ter Riet, Bas, Sweeney, Kate, DiPaolo, Courtney, Kieft, Rudo, Christodoulou, Evangelos, Perrakis, Anastassis, Simmons, Jana M., Hausinger, Robert P., van Luenen, Henri G.A.M., Rigden, Daniel J., Sabatini, Robert, Borst, Piet
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874643/
https://ncbi.nlm.nih.gov/pubmed/17389644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm049
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