The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase

Trypanosomatids contain an unusual DNA base J (β-d-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have searched for enzymes that catalyze J biosynthesis. We present evidence that a protein that binds to J...

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Hlavní autoři: Yu, Zhong, Genest, Paul-André, ter Riet, Bas, Sweeney, Kate, DiPaolo, Courtney, Kieft, Rudo, Christodoulou, Evangelos, Perrakis, Anastassis, Simmons, Jana M., Hausinger, Robert P., van Luenen, Henri G.A.M., Rigden, Daniel J., Sabatini, Robert, Borst, Piet
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874643/
https://ncbi.nlm.nih.gov/pubmed/17389644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm049
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