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MCAK and Paclitaxel Have Differential Effects on Spindle Microtubule Organization and Dynamics

Within the mitotic spindle, there are multiple populations of microtubules with different turnover dynamics, but how these different dynamics are maintained is not fully understood. MCAK is a member of the kinesin-13 family of microtubule-destabilizing enzymes that is required for proper establishme...

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Detalhes bibliográficos
Main Authors: Rizk, Rania S., Bohannon, Kevin P., Wetzel, Laura A., Powers, James, Shaw, Sidney L., Walczak, Claire E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655246/
https://ncbi.nlm.nih.gov/pubmed/19158381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0985
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