Coordinated Activation of Candidate Proto-Oncogenes and Cancer Testes Antigens via Promoter Demethylation in Head and Neck Cancer and Lung Cancer

BACKGROUND: Epigenetic alterations have been implicated in the pathogenesis of solid tumors, however, proto-oncogenes activated by promoter demethylation have been sporadically reported. We used an integrative method to analyze expression in primary head and neck squamous cell carcinoma (HNSCC) and...

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Main Authors: Smith, Ian M., Glazer, Chad A., Mithani, Suhail K., Ochs, Michael F., Sun, Wenyue, Bhan, Sheetal, Vostrov, Alexander, Abdullaev, Ziedulla, Lobanenkov, Victor, Gray, Andrew, Liu, Chunyan, Chang, Steven S., Ostrow, Kimberly L., Westra, William H., Begum, Shahnaz, Dhara, Mousumi, Califano, Joseph
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654921/
https://ncbi.nlm.nih.gov/pubmed/19305507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004961
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