Coordinated Activation of Candidate Proto-Oncogenes and Cancer Testes Antigens via Promoter Demethylation in Head and Neck Cancer and Lung Cancer

BACKGROUND: Epigenetic alterations have been implicated in the pathogenesis of solid tumors, however, proto-oncogenes activated by promoter demethylation have been sporadically reported. We used an integrative method to analyze expression in primary head and neck squamous cell carcinoma (HNSCC) and...

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主要な著者: Smith, Ian M., Glazer, Chad A., Mithani, Suhail K., Ochs, Michael F., Sun, Wenyue, Bhan, Sheetal, Vostrov, Alexander, Abdullaev, Ziedulla, Lobanenkov, Victor, Gray, Andrew, Liu, Chunyan, Chang, Steven S., Ostrow, Kimberly L., Westra, William H., Begum, Shahnaz, Dhara, Mousumi, Califano, Joseph
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654921/
https://ncbi.nlm.nih.gov/pubmed/19305507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004961
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